Consumer Reports Medical Guide - Mercaptopurine

Sulphametoxazole and trimetroprim (SMX/TMP) prophylaxis against PCP was given during induction and consolidation therapy but stopped prior to MT with oral methotrexate/6-mercaptopurine. Lowered resistance to infection Mercaptopurine can reduce the production of white blood cells by the bone marrow, making you more prone to infection. ( mercaptopurine )